Classic late parenchymal neurosyphilis, presenting as general paresis or tabes dorsalis, is due to extensive damage of the parenchyma in cortical regions of the brain or the spinal cord ...

Jun 1, 2011 · The onset is usually sudden, and an attack may last hours, days, or weeks, and usually subsides rapidly and completely." It occurred in about 12% of cases of tabes in the preantibiotic era. [7]

Subsequently in 1868, Charcot described neuropathic arthropathy in a patient with tabes dorsalis.