BACKGROUND: Direct reprogramming of fibroblasts to cardiomyocytes is a potentially curative strategy for ischemic heart ...

BACKGROUND: Fontan circulatory failure (FCF) is a chronic state in palliated single ventricle heart disease with high morbidity and mortality rates, including heart failure, multisystem end-organ ...

Comments and feedback on AHA/ASA Scientific Statements and Guidelines should be directed to the AHA/ASA Manuscript Oversight ...

BACKGROUND: Evaluation of whether dyspnea has a cardiac cause is essential. Guidelines from 2016 were reported to result in a ...

BACKGROUND: Hypertensive disorders of pregnancy (HDP) are a major cause of maternal morbidity and mortality and are associated with acute cardiac events in the peripartum period, as well as ...

BACKGROUND: In the phase 3 randomized controlled study ATTRibute-CM (Efficacy and Safety of AG10 in Subjects With Transthyretin Amyloid Cardiomyopathy), acoramidis, a transthyretin stabilizer, ...

A cardiac catheterization takes ≈45 minutes to complete. After a coronary angiogram, depending on the severity and pattern of any blockages detected in the coronary arteries, 3 common treatment paths ...

Childhood obesity has been referred to as a global pandemic. In both developed and developing countries, the prevalence of childhood obesity has significantly increased over the past 40 years. 1 ...

Gene Ontology analysis from differentially expressed genes revealed expected changes in cell cycle, metabolism, and contractility. In addition, mRNA splicing was among the top enriched differentially ...

The prognosis in patients with ST‐segment–elevation myocardial infarction (STEMI) has significantly improved in the past several decades, attributable to the routine use of primary percutaneous ...

Left ventricular (LV) systolic function is a powerful prognosticator of clinical outcome following percutaneous coronary intervention (PCI), 1, 2, 3 and patients who do not have in‐hospital LV ...

A total of 8 canines, with a weight of 35 to 40 kg and an age of 2.90±0.56 years, were randomized after the surgical procedure by the weight order into 2 observation groups: a 48-hour group (N=4) and ...