Here's how the Broncos can take down the 49ers on the road. Denver Broncos On SI Sean Payton gives high praise for 49ers coaching staff ahead of Week 4 matchup Head Coach Sean Payton had high praise for the coaching staff of the San Francisco 49ers.

The Denver Broncos will need to get the best of these matchups if they want to hand the San Francisco 49ers their first loss in Week 4.

The Denver Broncos battle the undefeated San Francisco 49ers on Sunday. Riding the highs of back-to-back comebacks, the Broncos are in pursuit of a third straight win. However, th

The Denver Broncos and San Francisco 49ers are facing off on CBS this Sunday at 4:25 p.m. ET at Levi's Stadium. Both teams are coming off wins, with Denver at 2-1, while the 49ers are one of the two undefeated NFC teams at 3-0.

NFL predictions, picks, score projections for Lions vs Panthers, Broncos vs 49ers, Chargers vs Seahawks, Chiefs vs Raiders, Dolphins vs Vikings, more.

That gives you eight opportunities to make some money with wagers on the outcomes of those games. If you are one who enjoys placing a wager or more, below are my betting picks for the moneyline, spread and total of those eight early games.

SportsLine expert Eric Cohen reveals his exact score projections for every Week 4 matchup to help with spread, money-line and over/under picks

NFL Week 4 TV map: Find every Sunday matchup

With the clock now at zero, here are our instant takeaways from the Colts' performance against Washington.

The Colts' receiver room got more bad news Saturday on the injury report ahead of Sunday's game in London vs the Commanders

Let's check in on who the experts have winning this Week 4 matchup between the Colts and Commanders.

A win in north London keeps a team in contention; a loss puts a team right back in desperation mode. 17 things to know about Colts vs Commanders

The No. 1 Brewers play the No. 4 Padres in Game 1 of their best-of-five National League Division Series in the 2026 playoffs. Follow for live updates.

The Brewers pulled out a tense, nailbiting 3-2 victory over the San Diego Padres in Game 1 of their National League Division Series on Oct. 3 to open their 2026 playoffs at American Family Field in Milwaukee.

The San Diego Padres' 26-man roster is set for the National League Division Series against the Milwaukee Brewers.

Fresh off a sweep of Chicago, San Diego faces tough bench dilemmas and pitching adjustments as they prepare to battle the top-seeded Brewers for a championship spot.

Lions head coach Dan Campbell said Friday that the team was "very much in" on trade talks for former Pittsburgh Steelers cornerback Joey Porter Jr.

After the Dallas Cowboys acquired cornerback Joey Porter Jr. from the Pittsburgh Steelers last week, it sounds like the trade market will continue to heat up.

The Pittsburgh Steelers reportedly traded cornerback Joey Porter Jr. to the Dallas Cowboys because of their refusal to include a second-year guarantee during contract discussions.

The Houston Texans have a date with Joey Porter Jr. on Sunday at Relaint Stadium.

The idle Oregon football team moved from No. 15 to No. 13 in the updated rankings released Sunday morning, as the Ducks continue to creep back toward the top 10 after dropping 12 spots to No. 18 on Sept.

How will the Big Ten's showing in Week 5 be reflected in the updated Week 5 Coaches Poll and AP Top 25 rankings? Here's what to know.

It was a rough week for the Coaches Poll after a few glaring mistakes. Here's its chance at redemption as we predict the Week 6 Top 25.

Here's a look at the updated US LBM Coaches Poll and AP Top 25 after Week 5 of the college football season: