Mechanisms for replicating DNA / G.S. Brush and T.J. Kelly -- Origins of DNA replication / M.L. DePamphilis -- Roles of transcription factors in DNA replication / P.C. van der Vliet -- Roles of ...

The DNA packed inside every human cell contains instructions for life, written in billions of letters of genetic code. Every time a cell divides, the complete code, divided among 46 chromosomes, must ...

Researchers at The University of Texas MD Anderson Cancer Center have developed a new imaging method, known as RF-SIRF, that ...

Scientists have discovered that a protein once thought to simply help load a factor necessary for the copying of DNA, actually plays a key role in ensuring fast and reliable replication—an insight ...

From the first unzip of the double helix to the final joining of DNA fragments, replication is a carefully coordinated process. Understanding it helps explain how life preserves its genetic code with ...

The MCM helicase is broadly bound across the genome, and its phosphorylation is antagonistically regulated by the kinase DDK and the phosphatase RIF1–PP1. TRESLIN–MTBP recognises the phosphorylated ...

A protein that prepares DNA for replication also prevents the replication process from running out of control, according to a new study by Weill Cornell Medicine researchers. The work, published Jan.

E. coli divides faster than it can replicate its genome, while simultaneously expressing its genes. Scientists recently revealed the intricate molecular coordination that makes this possible. “It’s as ...

Researchers at The University of Texas MD Anderson Cancer Center have identified a key enzyme—RNase H2—that helps ...

An asymmetric kleisin path breaks the symmetry of the SMC homodimer, ensuring unidirectional DNA translocation via a segment capture mechanism.