Nature

Genotype–phenotype correlation in Smith-Magenis syndrome: Evidence that multiple genes in 17p11.2 contribute to the clinical spectrum

Purpose: Smith-Magenis syndrome (SMS) is a complex disorder that includes mental retardation, craniofacial and skeletal anomalies, and behavioral abnormalities. We report the molecular and ...
Business Insider

Vanda Announces Positive Pivotal Study Results for HETLIOZ® (tasimelteon) in Patients with Smith-Magenis Syndrome

WASHINGTON, Dec. 10, 2018 /PRNewswire/ -- Vanda Pharmaceuticals Inc. (Vanda) (Nasdaq: VNDA) today announced that HETLIOZ ® (tasimelteon) improved sleep quality and increased sleep duration in patients ...
Monthly Prescribing Reference

FDA to Review Tasimelteon for Smith-Magenis Syndrome

Pexidartinib is an oral small molecule that is believed to work by inhibiting colony stimulating factor-1 receptor (CSF1R). The applications are supported by positive results from a double-masked, ...
Science Daily

Gene Responsible For Developmental Disorder Identified; Discovery Could Lead To New Therapies For Smith-Magenis Syndrome

Researchers at Michigan State University have identified the gene responsible for a developmental disorder known as Smith-Magenis syndrome (SMS), a discovery that could lead to new therapies for the ...
Nasdaq

FDA Approves HETLIOZ® (tasimelteon) for the Treatment of Nighttime Sleep Disturbances in Smith-Magenis Syndrome

WASHINGTON, Dec. 1, 2020 /PRNewswire/ -- Vanda Pharmaceuticals Inc. (Vanda) (Nasdaq: VNDA) today announced that the U.S. Food and Drug Administration (FDA) has approved HETLIOZ® (tasimelteon) capsule ...
Nasdaq

FDA Accepts and Grants Priority Review of Vanda's Applications for HETLIOZ® (tasimelteon) in the Treatment of Smith-Magenis Syndrome

WASHINGTON, Aug. 3, 2020 /PRNewswire/ -- Vanda Pharmaceuticals Inc. (Vanda) (Nasdaq: VNDA) today announced that the U.S. Food and Drug Administration (FDA) has accepted for priority review Vanda's ...
WTVD

Triangle moms trying to raise awareness of rare genetic syndrome called SMS

RALEIGH (WTVD) -- Coming up next week on November 17, families all over the world will be trying to raise awareness about a rare syndrome called Smith-Magenis Syndrome, or SMS. It's a developmental ...
ABC News

Ohio Mail Carrier Delivers Easter Act of Kindness to Teen With Smith-Magenis Syndrome

The Springfield, Ohio, mail woman helped the Easter Bunny deliver some treats. — -- A Springfield, Ohio, mother says she thought "it was fantastic" when her mail carrier delivered an Easter act ...
EurekAlert!

Reversing Smith-Magenis syndrome symptoms

Researchers report that restoring RAI1 gene expression levels during an early age-window partially reversed gene expression and social interaction deficits in a mouse model of Smith-Magenis syndrome ...
WDRB

Corn hole tournament at 3rd Turn Brewing raises awareness for Smith Magenis Syndrome

LOUISVILLE, Ky. (WDRB) -- A corn hole tournament in Oldham County raised awareness for a rare syndrome. 3rd Turn Brewing in Crestwood hosted the Nickels for Nico tournament for the 13th year. The ...
WGN-TV

Chicago Scene: One For The Kids – fundraiser for Smith-Magenis Syndrome

One for the Kids was established in 1993 by a group of concerned individuals who wanted to make a difference. Our first event was held at Old Oaks Golf course and raised a few thousand dollars. Since ...