The Giants host the 49ers at MetLife Stadium, with Big Blue — one week after Cam Skattebo’s gruesome injury — trying to keep hope for the year alive.

The New York Giants play host to the San Francisco 49ers on Sunday in a battle of teams missing multiple star players on both sides of the ball.

Since the injury avalanche hit the 49ers have managed to keep their heads above water and not suffer any bad losses. After losing in Week 8 to the Houston Texans on the road, the spotlight gets a little brighter for a group that has been pushed into bigger roles with a handful of injuries for San Francisco on both sides of the ball.

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The Giants vs. 49ers game will kick off shortly after 1 p.m. ET on Sunday, Nov. 2. The game will be played at MetLife Stadium in East Rutherford, New Jersey. Fans can listen to Giants vs. 49ers live on SiriusXM via channel 230 (New York broadcast) and 385 (San Francisco broadcast).

The San Francisco 49ers, led by quarterback Mac Jones, face the New York Giants, led by quarterback Jaxson Dart, on Sunday, Nov. 2, 2025 at MetLife Stadium in East Rutherford, N.J.

Christian McCaffrey and the San Francisco 49ers will face Jaxson Dart and the New York Giants in Week 9 of the NFL season.

Learn which TV channel or how to live stream the NFL Week 9 New York Giants and San Francisco 49ers game, Sunday, Nov. 2.