Week 17 is loaded with divisional matchups -- and could be your last chance to make up ground in your picks pool.

Vinnie Iyer is back for another season of fantasy football lineup advice, bringing his rankings and insights across all positions to help you make those tough Week 17 start 'em, sit 'em decisions based on matchups,

The runaway co-favorite Denver Broncos and New England Patriots — both +115 (i.e. risking $100 to win $115) to earn the top playoff position at Caesars/William Hill — both finally have challenging games. Denver hosts Green Bay as a 2.5-point underdog at most sportsbooks, while New England plays at home against Buffalo in a pick’em affair.