When a childhood brain tumor threatens the very wiring of sight, doctors have few options that actually protect vision. Now, a four-year follow-up study of children with optic pathway gliomas who once ...

Nearly 20% of children with NF1 develop pLGGs along the optic pathway, also known as NF1-associated optic pathway glioma (NF1-OPG). Despite many advances in cancer therapy, there are no definitive ...

Please provide your email address to receive an email when new articles are posted on . PHILADELPHIA — In this video, Michael Fisher, MD, discusses the results of a natural history study he presented ...

A Scientific Online Poster presented during the 2023 ARRS Annual Meeting, held April 16–20 on the island of Oahu, explained how the novel technique of three-dimensional (3D) slice-to-volume (SVR) MRI ...

The interplay between experimental autoimmunity and neural degeneration within optic pathways underpins the pathogenesis of optic neuritis and related demyelinating disorders. In preclinical models ...

Phase 1/2 study of elraglusib (9-ING-41), a small molecule selective glycogen synthase kinase-3 beta (GSK-3β) inhibitor, alone or with irinotecan, temozolomide ...

Treatment with 20 mg/m2 of lenalidomide in patients under 22 years old who have pilocytic astrocytomas and optic pathway gliomas appears to be safe and effective. Lenalidomide (Revlimid) at a dose of ...

Optic glioma is a brain tumor that grows slowly. Around 75% of diagnoses occur in children younger than 10 years old. Optic glioma accounts for approximately 5% of all childhood brain tumors. The ...

Increased Risk of Young-Onset Digestive Tract Cancers Among Young Adults Age 20-39 Years With Nonalcoholic Fatty Liver Disease: A Nationwide Cohort Study We performed a phase II trial of lenalidomide ...

It has been several months since Dr. Lane Rutledge, who was our colleague in the UAB NF Clinic, passed away unexpectedly, and her absence has been felt by those of us in the NF Clinic as well as by ...

An award-winning presentation during the 2023 ARRS Annual Meeting explained how the novel technique of three-dimensional (3D) slice-to-volume (SVR) MRI allows for precise delineation and measurement ...