Researchers at USF Health have discovered a new way opioid receptors can work that may lead to safer pain medications. Their findings show that certain experimental compounds can amplify pain relief ...

Struggling with alcohol cravings? Naltrexone targets the brain's reward center to minimize drinking urges and reduce harmful ...

Naloxone reversed more than 9,500 overdoses across Pennsylvania in the first nine months of 2025, the state’s Department of ...

New research reveals previously unknown ways opioid receptors can function, opening the door to safer pain treatments.

Neuropeptide FF (NPFF) is an endogenous peptide that plays a critical role in modulating opioid receptor function. Its dual capacity to influence both opioid-induced analgesia and tolerance has ...

Fentanyl does not need much room to kill. A dose the size of a few grains of salt can slow breathing until it stops. The drug ...

Scientists are testing a new kind of defense against the deadliest drug in the U.S. overdose crisis: a vaccine designed to ...

DETROIT – Narcan, also known as Naloxone, is a critical tool to fight overdoses. It rapidly reverses the potentially fatal effects of opioids in the body, but how does it do that? In over 30 years as ...

Opioid antagonists are medications people can take to treat opioid use disorder. They help by reducing withdrawal symptoms, addressing cravings, and managing overdoses. Doctors prescribe opioid ...

The title of this post comes from a San Francisco Chronicle article (April 6, 2023) [1] detailing why an alcoholic man sued Botanic Tonics, the makers of the “wellness drink” Feel Free, alleging it ...