In a new study published in Science Signaling titled, “Restoration of striatal neuroprotective pathways by kinase inhibitor treatment of Parkinson’s linked-LRRK2 mutant mice,” researchers from ...

Researchers say findings may have relevance to understanding cell biological pathways that contribute to nerve repair after injury or neurodegeneration.

Neuronal pathways originating from the orbitofrontal cortex (OFC) of the brain participate in different adaptive behaviors, but which pathways are used for distinct adaptive strategies remains unclear ...

During brain development, neurons can regulate their movement until they reach their final destination thanks to a "molecular switch" involving the protein Teneurin 4 (Ten4). This protein can guide ...

As knowledge of the development of neuronal pathways continues to grow, it also elucidates potential treatment modalities for neuronal degenerative diseases and injuries. Molecular and genetic ...

The APOE2 gene variant protects against Alzheimer's by enhancing DNA repair and preventing neuronal senescence.

Duke Health researchers found a relationship between immune response and neurological behavior after studying mice with a specific gene mutation, which exhibited signs of ADHD in response to an ...

A sequence of stress signals among specialized clean-up cells in the brain could at last reveal why some immune responses can cause significant nerve degeneration that results in the loss of memory, ...

Overview of the study. Researchers investigated the neural basis of how animals adapt to new environments and situations. To do this, they introduced a chemical ON/OFF switch in the orbitofrontal ...