Aortic dissection (AD) is a life-threatening cardiovascular emergency characterized by rapid onset and progression, with limited clinical intervention options. Lactate, a glycolytic metabolite, has ...

Mitochondria play a central role in cellular energy metabolism by converting nutrients into adenosine triphosphate (ATP) through oxidative phosphorylation. Beyond energy production, these organelles ...

Bonn, January 10, 2023 - Scientists led by Prof. Thomas Becker, Director of the Institute of Biochemistry and Molecular Biology at the University Hospital Bonn (UKB), have gained new insights into the ...

"The ATP synthase protein complex consists of a spinning rotor driven by the back transport of protons into the mitochondrial matrix. This part is connected to the enzyme's catalytic head by a stalk, ...

A single-atom nanozyme mimicking cytochrome c oxidase restores mitochondrial energy production in stem cells, shifting their ...