Voltage-gated proton channels are expressed in a variety of cell types and tissues. They were first described in snail neurons 1 and were subsequently found in many different species across phyla, ...

The alternative text for this image may have been generated using AI. Here, we have explored the possibility that subunit interaction sculpts function in the human Hv1 channel. We employed two ...

Researchers at the University of California, Irvine, have uncovered an unexpected molecular partnership that reshapes scientists’ understanding of how brain inflammation arises in Alzheimer’s disease.

Irvine, Calif., Oct. 23, 2025 — Researchers at the University of California, Irvine, have uncovered an unexpected molecular partnership that reshapes scientists’ understanding of how brain ...

Best known for churning out Aβ peptides, could amyloid precursor protein (APP) help keep protons flowing, too? In the October 28 PNAS, scientists led by Steve Goldstein at the University of California ...