G protein-coupled receptors (GPCRs) are seminal transducers of extracellular signals into intracellular responses, orchestrating intricate cascades that regulate cell proliferation, migration and ...

UNC postdoctoral Ajit Prakash explores how G proteins function as intracellular pH sensors and how this affects cell ...

It has been known for a long time that opioids release molecules called G proteins, which directly bind to calcium channels and make them "reluctant" to open. But how does this happen? It is as if ...

More information: Lijie Liu et al, Redox regulation of G protein oligomerization and signaling by the glutaredoxin WG1 controls grain size in rice, The EMBO Journal (2025). DOI: ...

A new single‑cell sequencing method is giving researchers a clearer view of how immune cells actually behave—capturing not just what they plan to do, but what they are doing in real time. The platform ...

Kirill Alexandrov Artificial intelligence–designed “smart” proteins can be programmed to turn on when they detect a certain ...

As a synthetic decapeptide structurally derived from gonadotropin-releasing hormone (GnRH), Triptorelin has long attracted research interest due to its unusually paradoxical signalling profile.