Study reveals how an RNA enzyme drives the postnatal switch from glucose to fatty acids in heart cells, highlighting ketogenesis as essential for metabolism. Study: The tRNA methyltransferase Mettl1 ...

Fatty acid oxidation (FAO) disorders comprise a heterogeneous group of inborn errors of metabolism that impair the mitochondrial capacity to convert fatty acids into energy. These inherited conditions ...

A multi-tissue proteomic atlas uncovers the shared and distinct molecular signatures of metabolic flexibility induced by intermittent fasting.

DDAH1 plays a critical role in hepatic lipid metabolism under fasting conditions by modulating FABP1 expression and AMPK/mTOR-mediated autophagy. The liver plays a central role in maintaining systemic ...

While C13 fatty acid remains elusive in human plasma, new findings reveal its microbial origins, unique metabolic pathways, and potential as a biomarker for understanding how diet and the gut ...

The role of FAO in cancer. FAO provides three essential substances for tumor metabolism, namely acetyl-CoA, NADPH, and ATP. Genes & Diseases publishes rigorously peer-reviewed and high quality ...