Most cancer genome studies have focused on mutations in the tumor itself and how such gene variants allow a tumor to grow unchecked. A new study takes a deep dive into inherited cancer mutations ...

The BRAF mutation affects a small percentage of non-small cell lung cancer (NSCLC) cases, making the cancer more difficult to treat. In recent years, advances in treatment have helped to improve ...

A detailed look at a mysterious mutation present in many different cancer types has revealed new drug targets that, when hit with a combo of well-known compounds, led to tumor cell death and prolonged ...

Dr. Marwan G. Fakih explains that KRAS mutations, found in 45% of patients with colorectal cancer, include the rare KRAS G12C mutation, leading to Lumakras approval. According to the National Cancer ...

Mutations within the Complex Proteins Associated With Set1 (COMPASS) family of histone lysine methyltransferases are frequently found in many human diseases including cancer. Increasingly, these ...

CURE spoke with Dr. Xiuning Le during the International Association for the Study of Lung Cancer (IASLC) 2025 World Conference on Lung Cancer. Lung cancer research has recognized the role of EGFR ...

Relationship Among DNA Damage Response Gene Alterations, Molecular Subtypes, and Survival Outcomes in Patients With Metastatic Bladder Cancer Treated on CALGB 90601 Sequencing data from 56,965 ...

A lung cancer diagnosis can feel frightening. And when a family member is diagnosed, you might wonder about your own risk, prompting you to ask if lung cancer is hereditary. Smoking tobacco accounts ...

Treatments based on genomic profiling can significantly extend survival for patients with advanced or rare cancer, but only ...

Cancer cells carry thousands of mutations, but not all mutations are created equal. Some make tumors highly visible to the immune system, while others help cancers hide. In this study, researchers ...