The discovery of a family with sequence similarity 102 member A (Fam102a) protein as a novel bone remodeling factor that regulates both osteoclast and osteoblast differentiation can aid the ...

An international collaboration study reveals how evolution and locomotion patterns, such as bipedalism, shaped bone structures through proteins present in the bone matrix. The findings of the study, ...

Birmingham researchers have shown that PEPITEM, a naturally-occurring peptide (small protein), holds promise as a new therapeutic for osteoporosis and other disorders that feature bone loss, with ...

Growth plates are areas of cartilage found at the ends of long bones. They play a role in the bone growth of children and teens. An injury to a growth plate can affect the development of a bone. While ...

HO or abnormal bone formation in soft tissues can restrict movement and cause long-term discomfort after surgery or injury. In a new study, researchers have identified two key proteins that help ...

Sustained hypoxia affects orthodontic tooth movement (OTM) by altering osteoclast and osteoblast differentiation, report researchers from Institute of Science Tokyo, Japan. Hypoxic conditions resulted ...

After serious injuries, burns, fractures, or major surgeries, the body normally repairs damaged tissues and restores movement. However, in some patients, the healing process takes an unexpected and ...

Living matter is not a passive material. A blood vessel wall, a hydrogel seeded with cells, a growing tissue: all are active networks whose architecture is continuously rewritten by encapsulated cells ...

Fam102a-Rbpjl axis in osteoblast differentiation reveals significant insights into bone remodeling and may aid the development of therapeutic strategies. Bones are the living tissue on which the human ...